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Từ điển Oxford Advanced Learner 8th

mis·for·tune [misfortune misfortunes] BrE [ˌmɪsˈfɔːtʃuːn] NAmE [ˌmɪsˈfɔːrtʃuːn] noun
1. uncountable bad luck
He has known great misfortune in his life.
We had the misfortune to run into a violent storm.
2. countable an unfortunate accident, condition or event
Syn: blow, Syn:disaster
She bore her misfortunes bravely.

Example Bank:
I had the misfortune to share a room with someone who snored loudly.
Misfortune struck before they had even left port.
The expedition was dogged by misfortune.

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